Healthy Aging at all Stages of Life

Healthy Aging at all Stages of Life

What in the GUT is going on? Gut Health, Butyrate and Your Wellness.

gut health

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Wondering where your GUT Microbiome is – it’s NOT in your stomach – it’s in your large and small intestines. Did you know that your intestinal tract is your largest immune system organ, where approximately 80% of your immune-producing cells live? Remember, if your cells are healthy, your body is healthy. Learn how gut health and butyrate can benefit your wellness

Your gut contains all the microbes that reside within your intestinal tract. And those microbes are comprised of bacteria, fungi, yeast, and viruses, according to staff at The Cleveland Clinic. And we’re not talking about a few hundred microbes — it’s estimated that about 100 trillion microbes are found inside the human body, with many of them residing in our gut.

How can we help our gut and overall health? Get more BUTYRATE!

What is Butyrate Acid?

Butyrate is a four-carbon, major short-chain fatty acid, named for their chemical structure, and is produced during gut flora-mediated through microbial fermentation of dietary fibers in the lower intestinal tract. Produced when “good” bacteria in your gut help your body break down dietary fiber in your large intestine (the colon).

Butyric acid, also known by the systematic name butanoic acid, is a straight-chain alkyl carboxylic acid with the chemical formula CH₃CH₂CH₂CO₂H. It’s an oily, colorless liquid with an unpleasant odor. Isobutyric acid is an isomer of butyric acid. Salts and esters of butyric acid are known as butyrates or butanoates.

What is an ISOMER: one of two or more chemical compounds or groups that have the same numbers of atoms of the same elements but differ in structure.

What is an ATOM: the basic unit of a chemical element (little, molecule).

What is a MOLECULE: a group of two or more atoms bonded together, of the same or different elements that are chemically bonded together, representing the smallest fundamental unit of a chemical compound that can take part in a chemical reaction. EXAMPLE: two atoms of hydrogen and one atom of oxygen react with each other and form one molecule of water.

A few reasons we need Butyrate; it provides anti-inflammatory properties, enhances intestinal barrier function and mucosal immunity. Want to know more? Keep reading.

How is Butyrate produced in the body?

Butyrate is produced in the body via microbial fermentation of dietary fibers in the lower intestinal tract.

Dietary fiber, also known as roughage or bulk, includes the parts of plant foods your body can’t digest or absorb. Unlike other food components, such as fats, proteins, or carbohydrates — which your body breaks down and absorbs — fiber isn’t digested by your body. Instead, it passes relatively intact through your stomach, the small intestine and colon and out of your body.

The amount of soluble and insoluble fiber is important, and it varies in different plant foods. To receive the greatest health benefit, eat a wide variety of high-fiber foods.

Fiber Classifications:

  • Soluble fiber: This type of fiber dissolves in water to form a gel-like material. It can aid lower blood cholesterol and glucose levels. Soluble fiber is found in oats, peas, beans, apples, citrus fruits, carrots, barley, and psyllium.
  • Insoluble fiber: This type of fiber promotes the movement of material through your digestive system and increases stool bulk, so it can be of benefit to those who struggle with constipation or irregular stools. Whole-wheat flour, wheat bran, nuts, beans, and vegetables, such as cauliflower, green beans and potatoes, are good sources of insoluble fiber

What’s the butyrate connection to cells and digestion, relating to our diet?

Butyric acid is well-known for supporting digestive health, reducing inflammation, lowering the risk of diseases, and promoting overall health. It plays a significant role in providing colon cells with the necessary energy to carry out their normal functions, as well as regulating blood sugar and cholesterol levels.

Butyrate is an important energy source for cells lining the mammalian colon, which is the longest part of the colon, a tube-like organ connected to the small intestine at one end and the anus at the other. Without butyrate, colon cells undergo autophagy (self-digestion) and die.

The colon removes water and some nutrients and electrolytes from partially digested food. You can replace and replenish lost nutrients to the entire body with Humic/Fulvic Acid Mineral (a food in supplement form that nourishes and hydrates promoting cellular health).

Since humans lack the enzymes to degrade the bulk of dietary fibers, these nondigestible carbohydrates pass through the upper gastrointestinal tract unaffected and undergo fermentation in the cecum and large intestine by the anaerobic cecal and colonic microbiota. Fermentation results in various metabolites, with short-chain fatty acids (SCFAs) comprising the major group.

To the microbial community, SCFAs are a vital waste product necessary for balancing redox equivalent production in the anaerobic environment of the gut.

Gut health and butyrate: What does butyrate do “to” your Body?

At the intestinal level, butyrate plays a regulatory role in transepithelial fluid transport, ameliorates mucosal inflammation and oxidative stress, reinforces the epithelial defense barrier, and modulates visceral sensitivity and intestinal motility.

What does butyrate do “in” your Body?

1. Reduce inflammation

Studies have shown that butyrate supplements may reduce the severity of disease-causing (pathogenic) bacterial infection by lessening inflammation. This could help prevent potentially fatal conditions such as sepsis.

Researchers have also linked low levels of butyrate to an increased risk of inflammatory intestinal disease and colorectal (colon) cancer.

2. Relieve gastrointestinal conditions

Butyrate supports the gut barrier, which keeps bacteria and other microbes from entering your blood. A sodium butyrate supplement may help with irritable bowel syndrome (IBS), diverticulitis and Crohn’s disease. Additionally, Humic/Fulvic Acid Mineral contains nutrients that improves gut health, including all major and trace minerals, electrolytes, silica (which boost collagen synthesis), pre-biotics and pro-biotics.

These all help to aid a nourished digestive tract and boost the ability of “good bacteria” to repopulate and form a healthy “MICROBIOME” environment. It is believed that the human microbiome is the main target of humic activity. Humic acids have a profound effect on healthy colonic microbiome.

According to the NIH (National Institute of Health), Microbe-derived butyrate plays an important role in both gut health and obesity of the host.

In one study, 66 adults with irritable bowel syndrome (IBS) who took a daily dose of sodium butyrate reported less abdominal pain. In another study, 9 of 13 people with Crohn’s disease reported improved symptoms after taking butyric acid every day for eight weeks.

3. Reduce colon cancer risk

Other research shows that a diet high in dietary fiber, which encourages butyrate production, could help lower your risk of colon cancer.

One laboratory study in human cancer cell lines found that sodium butyrate stopped the growth of colorectal cancer cells and caused cancer cell death (known as apoptosis). It’s also been shown to reduce damage caused by cancer or chemotherapy.

4. Increase insulin sensitivity

People with Type 2 diabetes often experience insulin resistance and obesity. Because butyrate helps produce gut hormones that regulate blood sugar levels, it may improve these symptoms. One study showed a potential link between butyrate production and lower insulin resistance.

5. Protect your brain

Butyrate-friendly foods and supplements may improve brain health. Researchers have shown that butyrate can protect your brain and improve its ability to adapt (known as plasticity). Early studies suggest it may help prevent or treat stroke, depression and other diseases that affect the brain, like Parkinson’s disease and Alzheimer’s disease.

6. Reduce cardiovascular disease risk

Some studies suggest that butyrate may help protect your body against widespread cardiovascular diseases. Heart and blood vessel problems can increase your risk of:

  • Atherosclerosis
  • Heart failure
  • High blood pressure
  • Stroke

7. Enhance Sleep

The promise of butyrate extends all the way to your bedroom. Emerging evidence suggests that your gut bacteria are a source of signals that promote sleep. A 2019 study showed that mice and rats who received butyrate showed a dramatic increase in non-rapid-eye movement (NREM) sleep for four hours after treatment. NREM includes important stages of sleep for your physical and mental health.

How do you increase butyrate in the Body?

gut health and butyrate

The best way to supercharge your gut microbiome and to produce butyrate is to eat a high-fiber diet, that includes sufficient sources of resistant starch and pectin. This means eating a diet rich in plant-based foods such as wholegrains, vegetables, fruits, nuts, seeds, and legumes.

Resistant starch is a type of nutrient that may help your body with digestion, weight loss, disease prevention, and other important functions. It also creates an environment in which beneficial bacteria thrive. You can increase the resistant starch content of foods such as potato, pasta and rice by cooking and then cooling them overnight for use in salads.

Low levels of butyrate have been linked to an increased risk of inflammatory intestinal disease and colorectal (colon) cancer.

How much butyric acid do you need?

According to the United States Department of Agricultures (USDA), the recommended intake for dietary fiber is 25 grams per day for women and 35 grams per day for men, or about 28 grams as part of a 2,000-calorie daily diet. Your value may be higher or lower, depending on your calorie intake. This fiber should be a mixture of soluble (butyrate-generating) and insoluble sources.

Wondering what foods are high in butyrate?

Legumes (beans, peas, and soybeans), fruits, nuts, cereals, and whole grains are good sources of dietary fibers. It is also found in butter and cheese. Remember Pecorino is the healthiest cheese. Great for the heart.

Here are a few food items with meal prebiotics that can boost your butyrate-producing potential.

RESISTANT STARCH SOURCE:

  • Rolled Oats
  • Cooked and Cooled Pasta
  • Sweet Potato
  • Lentils
  • Hummus

PECTIN SOURCES:

  • Strawberries
  • Raspberries
  • Blueberries
  • Kiwi
  • Zucchini
  • Eggplant
  • Cherry Tomatoes
  • Carrot
  • Peas
  • Tomatoes
  • Pasta

HUmineral™ is committed to delivering consumers information and quality products that are from organic, natural and chemical-free sources in the form of whole foods and whole food supplements.

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